Ca2+ is an important messenger which mediates several physiological functions, including muscle contraction, fertilisation, heart regulation and gene transcription. One major way its cytosolic level is raised is via a G protein coupled receptor (GPCR) mediated release from intracellular stores. GPCR’s are the target of approximately 50% of all drugs in clinical use.

Price: 19,499 (base model)Samsung’s latest smartphone in the Galaxy M series is the Galaxy M31s. It’s also the most expensive Galaxy M phone so far. Galaxy M31s starts at 19,499 and goes up to 21,499. Honest non snarky question, why does it take 1,400 employees to sell mail order glasses, which are essentially a quasi commodity product?Ideally, a whole lot of them would be brilliant people working on improving design, improving support, and improving the supply chain. Most likely, a lot of them are working on or administering the retail storefronts, which in 2018 is a somewhat a marketing function. This misalignment vector generally expresses itself through the Marketing, PR, and legal teams.

“Walking pneumonia” sounds like it could be the name of a sci fi horror flick. But it’s actually the least scary kind of pneumonia. It can be milder than the other types, and you usually don’t have to stay in the hospital. Drive slowly and carefully. Road conditions are dangerous. Power lines are dangling; traffic lights are not working.

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WH Official Threatened Reporter over Story on His Relationship, Accused Her of Sexual JealousyA White House official threatened Politico reporter Tara Palmeri after she pursued a story on the official’s relationship with a different reporter at Axios, Vanity Fair revealed on Friday. Palmeri reached out to Axios reporter Alexi McCammond on January 20 to ask for comment on McCammond’s relationship with incoming Deputy Press Secretary TJ Ducklo. A male Politico reporter reached out to Ducklo for comment, but Ducklo subsequently called Palmeri and, in an off the record conversation, threatened to ruin her reputation if the story was published.

Spreading rumours that Sushant Singh Rajput came up with the idea of the game FAU G is now against court orders. A civil court in Mumbai on Thursday passed an interim order to restrict people from spreading rumours that FAU G and Goqii Vital 3.0 were conceptualised by actor Sushant Singh Rajput, who died in June. The order, a copy of which is with Gadgets 360, restrains users from “posting and reposting tweets, sharing posts, sending messages and videos on various social media platforms” including Facebook, LinkedIn, Twitter, and YouTube.